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Cardiac markers are biomarkers measured to evaluate heart function. Most of the early markers were identified as enzymes. However, not all of the markers currently used are enzymes. Physicians use cardiac markers in two ways-to diagnose a cardiac event in the hospital emergency room or to evaluate the risk of a cardiovascular event occurring. The traditional markers are CK-MB, troponin, and myglobin. There cardiac biomarkers are one of the fastest growing markets involving clinical immunoassay testing. Cardiac biomarkers have been the new frontier in cardiovascular and metabolic disease diagnosis. Recently, BNP and D-dimer is very popular with important clinical meaning.
According to the CDC, Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in the U.S. accounting for more than 40% of all deaths and nearly six million hospitalizations annually. TriMark estimates that the market in the U.S. for rapid POC cardiac markers was $413 million in 2010. This market is projected to grow to $795 million in 2016. In EU, Troponin testing has reached the upper strata of the product life cycle.